Life science leaders have to stay abreast of new initiatives and possess insightful perspectives on the industry’s future in the upcoming decade. They have to guide and lead teams while mitigating potential risks. Making informed decisions necessitates the ability to sift through vast amounts of data and information. Dr. Safwan Kezbor (Clinical development leader with current role as Senior Medical Director at Shionogi Inc.) understands the latest scientific advancements and methodologies in the field. He effectively navigates the ever-changing landscape of the life sciences industry. Emboldened by unique talent and vision, Dr. Kezbor now spearheads extensive global clinical studies and finds immense fulfillment in this chosen path, day after day.
Dr. Safwan Kezbor’s Broad Expertise
Upon completion of his medical studies and attainment of his M.D. degree, Dr. Kezbor embarked on postgraduate clinical research studies across prestigious institutions within New York City, such as Columbia University and Mount Sinai Hospital. Subsequently, he had the privilege of gaining clinical drug experience within the earlier phases of clinical development by joining an early-phase clinical research development organization. The importance of such early-phase studies cannot be overstated as they serve as a crucial bridge between non-clinical and clinical studies, ultimately enabling the submission of the Investigational New Drug (IND) application. It is noteworthy that obtaining such knowledge in academia is challenging given that clinical trials typically concentrate on later phases of clinical studies (Phase 3 and 4).
Dr. Safwan Kezbor’s unique professional background and experience in leading clinical research across the three primary stakeholders for clinical trial conduct, namely, the pharma industry, Clinical Research Organizations, and Academia, has given him a comprehensive understanding of the research process globally. It has been a privilege for him to lead all phases of clinical programs, from Phase 1 to Phase 4, and he believes this experience has equipped him with the necessary skills to guide and lead these stakeholders constructively.
Dr. Safwan Kezbor’s professional endeavors have traversed a diverse array of therapeutic domains, encompassing cardiovascular and metabolic diseases (including weight management and obesity), rare diseases, immunology, and infectious diseases, with a notable opportunity to focus on COVID-19. Within each distinct area, Dr. Kezbor has encountered unique challenges, fostering the development of skills in knowledge application and transfer across therapeutic boundaries. This breadth of experience underscores Dr. Kezbor’s adaptability and versatility within the realm of clinical research.
Clinical Expertise Meets Strategic Vision
Diverging from traditional bedside care towards the clinical development sphere, Dr. Kezbor reflects on the intriguing trajectory of his medical career. Two pivotal factors steered this shift. Firstly, the profound impact of addressing new diseases and unmet medical needs resonated deeply, offering a chance to effect change on a global scale. Secondly, invaluable guidance from esteemed mentors highlighted Dr. Kezbor’s innate aptitude for data analysis and clinical protocol design, minimizing risks, and maximizing success probabilities in clinical programs.
In the life sciences industry, Dr. Safwan Kezbor believes that the distinctive blend of clinical acumen, strategic foresight, and commitment to addressing unmet medical needs sets them apart from peers. This multifaceted approach not only drives innovation but also ensures the delivery of impactful therapies that improve patient outcomes on a global scale.
Dr. Safwan Kezbor attributes this to two essential skills in the life sciences field: critical thinking and strategic planning, both of which underpin the discovery and delivery of innovative treatments and therapies. Critical thinking and the ability to analyze complex data are paramount in designing appropriate clinical studies for various diseases and conditions. Conversely, strategic planning ensures that treatments are developed and implemented to maximize their impact and benefit patients. Together, these elements significantly contribute to advancing medicine’s understanding and enhancing health outcomes worldwide.
A New Era of Collaboration
Dr. Safwan Kezbor observes that the ongoing technological revolution is significantly reshaping the behaviours and expectations of key stakeholders within the life sciences industry. These stakeholders encompass pharmaceutical companies, regulatory agencies, and patients, all seeking more innovative and efficient clinical trial designs. These designs aim to expedite the development of new therapies while enhancing accessibility for patients, focusing on critical factors, and allowing greater flexibility in assessments, geographic locations, and local site requirements.
This paradigm shift has propelled the industry towards more patient-centered approaches, anticipated to offer superior care and treatment. Consequently, the life sciences sector is redefining clinical trial design and data collection and analysis methods, emphasizing quality by design and integrating modern technologies to yield improved outcomes.
Shaping the Future
Highlighting the remarkable progress achieved in gene therapy and cancer treatment, Dr. Safwan Kezbor asserts that this momentum is expected to continue into the next decade. These advancements hold promise for delivering effective solutions to patients. Furthermore, Dr. Kezbor underscores the significance of advancements in Real-world Evidence (RWE) and health economics and outcomes research (HEOR). These methodologies are gaining traction and playing pivotal roles in shaping the future of clinical studies and evidence generation.
By furnishing additional evidence and selecting clinically relevant endpoints, these methodologies are opening new avenues to enhance patient outcomes. Embracing RWE and HEOR fosters a collaborative environment where healthcare professionals, regulatory agencies, and patients collaborate to pave the way for a brighter future for all.
Dr. Safwan Kezbor’s Perspective on Adaptability and Growth
Dr. Safwan Kezbor views challenges as valuable opportunities for expanding perspectives and exploring new possibilities that may otherwise remain unexplored. One significant challenge lies in the complex nature of clinical development within the life sciences field. This complexity necessitates agility and adaptability, as emerging data and new information continually shape the clinical program. While it’s crucial to formulate a long-term plan spanning five years, Dr. Safwan Kezbor emphasizes the importance of remaining open-minded and responsive to evolving circumstances. Recognizing the constant evolution of disease understanding and treatment landscapes, he is dedicated to staying ahead of the curve and adjusting approaches as new insights emerge.
In the realm of life sciences, Dr. Safwan Kezbor recognizes the multitude of unmet medical needs awaiting solutions. As a physician, he is motivated by the desire to alleviate the burdens of health issues afflicting patients. The expansive possibilities within life sciences have allowed Dr. Kezbor to pursue this noble goal on a broader scale. Driven by the imperative to discover innovative, efficient, and convenient treatments that enhance the patient journey and bolster the health and productivity of society. This remains the primary driving force propelling Dr. Kezbor forward.
Growth Mindset for Life Sciences Leadership
In the past decade, pharma organizations have acknowledged the significant transformation within the life science industry. Scientists and researchers have achieved groundbreaking discoveries, unveiled new pathways, and conducted clinical studies resulting in the creation of innovative and efficacious products. However, to maintain a leading position, it is imperative to adopt an open and inquisitive mindset. Embracing change and exploring new ideas, even amidst risks and occasional setbacks, is essential. Through such endeavors, Shionogi Inc. believes it can foster innovation and propel progress more efficiently.
To become an effective leader in the life sciences, Dr. Kezbor emphasizes the importance of fostering curiosity and honing critical thinking skills. He encourages individuals not to shy away from taking risks and embracing mistakes, as they often yield valuable lessons and personal development. Approaching life with an open mind and consistently challenging oneself to think innovatively is key. With constructive thinking and a growth mindset, Dr. Kezbor believes individuals can attain greatness and unlock their full potential in their life science careers.
Making a Difference in Patient Care
Dr. Safwan Kezbor finds immense fulfillment in hearing stories about how innovative treatments have positively transformed the lives of patients and their families. While the journey in clinical drug development poses significant challenges, requiring years of meticulous testing to guarantee the safety and efficacy of each new drug, the satisfaction derived from witnessing the positive impact of their work on patients and society makes it all worthwhile for Dr. Kezbor. Leading and being part of a team that is genuinely making a difference in people’s lives is regarded as a privilege by Dr. Kezbor.
Holding an optimistic outlook on the future of humanity, Dr. Kezbor envisions a world where the impact of diseases on patients and society is minimized through advancements in medical research and the development of innovative treatments. He believes that the prospect of longer and healthier lives, free from the burdens of chronic conditions without medical solutions, will empower individuals to pursue their aspirations and fulfill their potential. Committed to lifelong learning, Dr. Kezbor is dedicated to utilizing their skills and knowledge to contribute towards realizing this vision.
Effective Leadership in Life Science and Clinical Development
Motivating a team in the life sciences, particularly within clinical drug development, presents both simplicity and complexity for Dr. Kezbor. On one hand, the task is straightforward, knowing that work directly impacts individual health and wellness. It allows people to navigate life with fewer physical limitations. However, the challenge arises from realizing that the outcomes of efforts may not manifest immediately, often taking years to achieve success. Therefore, Dr. Safwan Kezbor emphasizes the importance of maintaining an unwavering focus on long-term objectives, with daily efforts aimed at the overall success of innovative treatments. It is vital to remember that the work undertaken today lays the foundation for a healthier and more fulfilling tomorrow, where individuals can thrive.
